Enzymatic synthesis of a catechin conjugate of polyhedral oligomeric silsesquioxane and evaluation of its antioxidant activity |
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| Authors: | N Ihara M Kurisawa J E Chung H Uyama S Kobayashi |
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| Institution: | (1) Department of Materials Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan |
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| Abstract: | The antioxidant activity of catechin was amplified by conjugation with amine-terminated polyhedral oligomeric silsesquioxane (POSS) using horseradish peroxidase as catalyst. Compared to intact catechin, the scavenging activity of the POSS-catechin conjugate against superoxide anion was greatly improved. In addition, the conjugate strongly inhibited xanthine oxidase activity. |
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