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Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity
Authors:Tinoush Moulaei  Shilpa R. Shenoy  Barbara Giomarelli  Cheryl Thomas  James B. McMahon  Zbigniew Dauter  Barry R. O'Keefe  Alexander Wlodawer
Affiliation:1. Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA;2. Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA;3. SAIC-Frederick Inc., National Cancer Institute, Frederick, MD 21702-1201, USA;4. Synchrotron Radiation Research Section, Macromolecular Crystallography Laboratory, National Cancer Institute, Argonne National Laboratory, Argonne, IL 60439, USA
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