Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. |
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| Authors: | D G Phinney G Kopen W Righter S Webster N Tremain D J Prockop |
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| Institution: | Center for Gene Therapy, MCP Hahnemann University, Philadelphia, Pennsylvania 19102, USA. phinney@auhs.edu |
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| Abstract: | Human marrow stromal cells (MSCs) were isolated from posterior illiac crest marrow aspirates obtained from 17 healthy donors, ages 19-45 years, with no apparent physical disability. First passage hMSCs exhibited growth rates in vitro that varied up to 12-fold between donors. No correlation between growth rate and the age or gender of the donor was evident (P
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