An Efficient Strategy for the Determination of the Three-Dimensional Architecture of Ribonucleoprotein Complexes by the Combination of a Few Easily Accessible NMR and Biochemical Data: Intermolecular Recognition in a U4 Spliceosomal Complex |
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| Authors: | Ping Li John Kirkpatrick Teresa Carlomagno |
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| Affiliation: | 1 Department of NMR-Based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany
2 European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany |
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| Abstract: | |
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| Keywords: | RNP, ribonucleoprotein hPrp31, human Prp31 SL, stem-loop K-turn, kink-turn NOE, nuclear Overhauser enhancement iRMSD, interface RMSD SA-MD, simulated annealing-molecular dynamics |
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