WNTs in synapse formation and neuronal circuitry |
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Authors: | Park Mikyoung Shen Kang |
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Affiliation: | Center for Functional Connectomics, Brain Science Institute, Seoul, Korea. mpark@kist.re.kr |
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Abstract: | Wnt proteins play important roles in wiring neural circuits. Wnts regulate many aspects of neural circuit generation through their receptors and distinct signalling pathways. In this review, we discuss recent findings on the functions of Wnts in various aspects of neural circuit formation, including neuronal polarity, axon guidance, synapse formation, and synaptic plasticity in vertebrate and invertebrate nervous systems. |
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Keywords: | neurobiology neuronal circuits synapse formation Wnts |
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