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N-isobutyl-trans-2-trans-4-eicosadienamide and other alkaloids of fruits of Piper guineense
Authors:Ivan Addae-Mensah  Frank G Torto  Isaac V Oppong  Ian Baxter  Jeremy KM Sanders
Institution:1. Department of Chemistry, University of Ghana, Legon, Ghana South Africa;2. University Chemical Laboratories, Lensfield Road, Cambridge CB2 1EW, England
Abstract:A novel alkaloid, N-isobutyl-trans-2-trans-4-eicosadienamide, has been isolated from the fruits of Piper guineense and fully characterized. The structure of the compound has been confirmed by an unambiguous synthesis of the tetrahydro derivative. The known alkaloid, δαβ-dihydropiperine has also been isolated and the position of the double bond in this compound confirmed by the use of an NMR shift reagent.
Keywords:Piperaceae  alkaloids
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