High levels of oncomiR‐21 contribute to the senescence‐induced growth arrest in normal human cells and its knock‐down increases the replicative lifespan期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

High levels of oncomiR‐21 contribute to the senescence‐induced growth arrest in normal human cells and its knock‐down increases the replicative lifespan

Authors:	Lucia Terlecki‐Zaniewicz Carina Schreiner Klaus Fortschegger Martina W.‐F. Chang Matthias Hackl Rossella Monteforte Harald Kühnel Markus Schosserer Florian Gruber Erwin Tschachler Marcel Scheideler Regina Grillari‐Voglauer Johannes Grillari Matthias Wieser

Affiliation:	1. Department of Biotechnology, BOKU‐VIBT University of Natural Resources and Life Sciences Vienna, , 1190 Vienna, Austria;2. CCRI ‐ Children's Cancer Research Institute, , 1090 Vienna, Austria;3. Institute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, , A‐1210 Vienna, Austria;4. Department of Dermatology, Medical University of Vienna, , A‐1090 Vienna, Austria;5. C.E.R.I.E.S. ‐ Centre de Recherches et d'Investigations Epidermiques et Sensorielles, , 92200 Neuilly‐sur‐Seine, France;6. Institute for Genomics and Bioinformatics, Graz University of Technology, , 8010 Graz, Austria;7. Evercyte GmbH, , 1190 Vienna, Austria;8. Austrian Centre of Industrial Biotechnology (ACIB GmbH), , 1190 Vienna, Austria

Abstract:

Keywords:	CDC25A CDK2 cellular senescence hyperoncogenic signal microRNA miR‐21 NFIB p21