| 四君子汤保护骨损伤后小鼠肠道细菌易位及促进骨修复的研究 |
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| 引用本文： | 唐华羽,吴庆田,李玉芝,杨景云,侯霞.四君子汤保护骨损伤后小鼠肠道细菌易位及促进骨修复的研究[J].中国微生态学杂志,2009,21(7). |
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| 作者姓名： | 唐华羽 吴庆田 李玉芝 杨景云 侯霞 |
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| 作者单位： | 1. 佳木斯大学临床医学院,黑龙江,佳木斯,154002
2. 佳木斯大学基础医学院,黑龙江,佳木斯,154002 |
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| 摘 要： | 目的 观察四君子汤对骨损伤后小鼠免疫功能和细菌易位的影响,探讨中药在提高免疫力及预防感染方面的作用.方法 通过制备小鼠股骨骨损伤模型,骨损伤后在腹腔注射抗生素的同时辅以四君子汤,观察四君子汤对小鼠吞噬细胞功能的影响和细菌易位的控制.结果 骨损伤经四君子汤治疗后肝脏细菌易位明显减少(P＜0.01);吞噬细胞功能显著增强(P＜0.01);因有效控制了感染使骨修复过程加速.结论 四君子汤能够保护骨损伤后小鼠肠道细菌易位和促进骨修复.
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| 关 键 词： | 四君子汤 骨损伤 肠道细菌 易位 骨修复 |
Si Jun Zi soup prevent bacterium migration from after fracture of mice and promote fracture healing |
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| TANG Hua-yu,WU Qing-tian,LI Yu-zhi,YANG Jing-yun,HOU Xia.Si Jun Zi soup prevent bacterium migration from after fracture of mice and promote fracture healing[J].Chinese Journal of Microecology,2009,21(7). |
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| Authors: | TANG Hua-yu WU Qing-tian LI Yu-zhi YANG Jing-yun HOU Xia |
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| Abstract: | Objective To watch inhibition of Si Jun Zi soup to bacterium migration and improvtion immune systems, research function of traditional Chinese medicine to improve immune function and prevent infection.Method By doing fracture model of mice, treatment antibacterial and Si Jun Zi soup orally, watch immune fuction improve and inhibition bacterium migration.Result Bacterium migration of liver was decreased(P＜0.01), immune cells function was increased(P＜0.01),fracture healing was accelerated. Conclusion Si Jun Zi soup can inhibition bacterium migration and promote fracture healing. |
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| Keywords: | Si Jun Zi soup Bone fracture Bacterium migration Fracture healing |
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