Cyclin B is associated with centrosomes in Drosophila mitotic cells. |
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Authors: | A Debec C Montmory |
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Institution: | Unité Associée du CNRS 1135, Université Pierre et Marie Curie, Paris, France. |
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Abstract: | We have studied by way of confocal laser scanning microscopy the subcellular localization of cyclin B in Drosophila-cultured cells and report here evidence that a part of the cyclin B cell pool is closely associated with the centrosome. This cyclin B centrosomal signal is strong in prophase and metaphase but disappears during anaphase. Moreover, the signal is absent in the acentriolar Drosophila cell line 1182-4. These results put forward additional arguments suggesting that the centrosome plays an important role in the control of the cell cycle. |
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Keywords: | cyclin B centrosome centrioles Drosophila |
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