Paracoccidioides brasiliensis pancreatic destruction in Calomys callosus experimentally infected |
| |
| Authors: | Rogério M Fortes André Kipnis Ana Paula Junqueira-Kipnis |
| |
| Affiliation: | (1) Laborat?rio de Imunopatologia das Doen?as Infecciosas, Departamento de Microbiologia, Imunologia, Parasitologia e Patologia, Instituto de Patologia Tropical e Sa?de P?blica, Universidade Federal de Goi?s, (Research Center for Tropical DiseasesFederal University of Goias) Goiania, Gois, Brasil |
| |
| Abstract: | Background The wild rodent Calomys callosus is notably resistant to Trypanosoma cruzi infection. In order to better characterize this animal model for experimental infections, we inoculated C. callosus intraperitoneally with Paracoccidioides brasiliensis, a thermally dimorphic fungus that causes a chronic disease with severe granuloma formation in the mouse and humans. The dissemination of P. brasiliensis cells through the lungs, liver, pancreas, and spleen was assessed by histological analysis. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
