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Genetic profiling of human cell lines used as in vitro model to study cardiovascular pathophysiology and pharmacotoxicology
Authors:Elise Jeannesson  Gérard Siest  Mohamed Zaiou  Hind Berrahmoune  Christine Masson  Sophie Visvikis-Siest
Affiliation:1.Equipe Génétique Cardiovasculaire,INSERM, CIC 9501,Nancy,France;2.Faculté de Pharmacie,Nancy-Université,Nancy,France;3.Equipe Inserm Génétique Cardiovasculaire, Faculté de Pharmacie,INSERM-CIC 9501,Nancy,France
Abstract:

Background  

Cell lines are widely used to monitor drug pharmacokinetics and pharmacodynamics and to investigate a number of biochemical mechanisms. However, little is known about the genetic profile of these in vitro models.
Keywords:
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