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Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
Institution:1. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA;2. Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA;3. Endocrine Research, Mayo Clinic, Rochester, MN 55905, USA;4. Schulze Center for Novel Therapeutics, Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA;5. Department of Biochemistry & Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA
Abstract:
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  • Keywords:pancreatic cancer  Invasion  cathepsin B  DOCK8  lysosome  metastasis  matrix degradation  CP: Cancer
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