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Senescence of bone marrow fat cells: A new clue for glucocorticoid-induced bone deterioration
Affiliation:1. Research Center for Computer-aided Drug Discovery, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China;2. Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Shenzhen 518055, China;1. Guangzhou Laboratory, Guangzhou, Guangdong 510005, China;2. Bioland Laboratory, Guangzhou, Guangdong 510320, China;3. State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China;4. LipidALL Technologies Company Limited, Changzhou, Jiangsu 213022, China;5. Department of Pathology and Pathophysiology and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China;6. The Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Health Science Center, Peking University, Beijing 100191, China;7. The State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100005, China;1. Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250021, China;2. Shandong Clinical Research Center of Diabetes and Metabolic Diseases, Jinan, Shandong 250021, China;3. Shandong Institute of Endocrine and Metabolic Diseases, Jinan, Shandong 250021, China;4. Shandong Engineering Laboratory of Prevention and Control for Endocrine and Metabolic Diseases, Jinan, Shandong 250021, China;5. Shandong Engineering Research Center of Stem Cell and Gene Therapy for Endocrine and Metabolic Diseases, Jinan, Shandong 250021, China;6. Department of Ultrasound, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province 230022, China;7. Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China;8. Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA;9. Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China;1. Department of Endocrinology and Nutrition, Research Unit, Institut d’Investigació Sanitària Pere Virgili (IISPV), Hospital Universitari de Tarragona Joan XXIII, Tarragona 43005, Spain;2. CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid 28029, Spain;3. Department of Medicine and Surgery, Universitat Rovira i Virgili (URV), Reus 43201, Spain;4. Institut d’Oncologia de la Catalunya Sud, Hospital Universitari Sant Joan de Reus, IISPV, Reus 43204, Spain;5. Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Madrid 28029, Spain;6. Departament de Ciències Fisiològiques, Universitat de Barcelona, IDIBELL, Hospitalet de Llobregat, Barcelona 08907, Spain;7. Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, IISPV, Tortosa 43500, Spain;8. General and Digestive Surgery Service, Hospital Sant Pau i Santa Tecla, Institut d''Investigació Sanitària Pere Virgili, Tarragona 43003, Spain;9. Institut d’Investigacions Biomèdiques (IIB) Sant Pau, Barcelona 08041, Spain;10. Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona 08193, Spain;11. Department of Diabetes, Endocrinology and Nutrition, Institut d’Investigació Biomèdica de Girona (IdIBGi), Salt 17190, Spain;12. CIBER Fisiopatología de la Obesidad y Nutrición (CB06/03/010), Instituto de Salud Carlos III, Madrid 28029, Spain;13. Department of Medical Sciences, School of Medicine, University of Girona, Girona 17004, Spain;14. Department of Endocrinology and Nutrition, Hospital Universitari Bellvitge – IDIBELL, Hospitalet de Llobregat, Barcelona 08907, Spain;1. State Key Laboratory for Oncogenes and Related Genes, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai 200001, China;2. Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China;1. Department of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China;2. Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China;3. Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430071, PR China;4. Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China;1. Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, 85764 Neuherberg, Germany;2. German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany;3. Research Unit NeuroBiology of Diabetes, Helmholtz Zentrum München, 85764 Neuherberg, Germany;4. Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany;5. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Medical Drive 8, Singapore 117597, Singapore;6. Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia;7. Institute of Developmental Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany;8. Developmental Genetics, TUM School of Life Sciences, Technische Universität München, Freising-Weihenstephan, Germany;9. Deutsches Institut für Neurodegenerative Erkrankungen (DZNE) Site Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany;10. Munich Cluster for Systems Neurology (SyNergy), Adolf-Butenandt-Institut, LudwigMaximilians Universität München, Feodor-Lynen-Str. 17, 81377 Munich, Germany;11. Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH, USA;12. Division of Neurobiology of Diabetes, TUM School of Medicine, Technical University of Munich, 80333 Munich, Germany;13. Division of Metabolic Diseases, Technische Universität München, 80333 Munich, Germany;14. Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, 80336 Munich, Germany
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