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Habitual daily intake of a sweet and fatty snack modulates reward processing in humans
Affiliation:1. Max Planck Institute for Metabolism Research, Cologne, Germany;2. Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany;3. Fralin Biomedical Research Institute at Virginia Tech Carilion & Department of Human Nutrition, Foods, and Exercise, College of Agriculture and Life Sciences, Roanoke, VA, USA;4. Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany;5. Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) & Excellence Center for Medical Mycology (ECMM), Faculty of Medicine and University Hospital Cologne, Cologne, Germany;6. Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology, Zurich, Switzerland;7. Policlinic for Endocrinology, Diabetes and Preventive Medicine (PEPD), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany;8. Department of Neuroradiology, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany;9. German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany;10. Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany;11. Modern Diet and Physiology Research Center, New Haven, CT, USA;12. Yale University School of Medicine, Department of Psychiatry, New Haven, CT, USA
Abstract:
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  • Keywords:obesity  high-fat diet  dopamine  reinforcement learning  neural plasticity  reward  value  preference  taste  fMRI  prediction error
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