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Functional dendritic polymer architectures as stimuli-responsive nanocarriers
Authors:Marcelo Calderón  Mohiuddin A Quadir  Miriam Strumia  Rainer Haag
Institution:1. Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany;2. Departamento de Química Orgánica, Universidad Nacional de Córdoba, 5000 – Córdoba, Argentina
Abstract:Stimuli-responsive polymer architectures are molecular systems which evolve with an external signal. The observed changes are mainly decomposition, isomerization, polymerization, activation, supramolecular aggregation, and structural modifications of these molecules. The external stimuli, which can be combined in order to provoke these molecular changes, are numerous. In this review, we have chosen to present an overview on different mechanisms to impart responsiveness to dendritic polymers, with the particular aim of delivery and release of bioactive molecules.
Keywords:Stimuli responsive  Dendritic architectures  Nanocarriers  Drug encapsulation  Polymer therapeutics
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