Immunohistochemical localization of mu opioid receptor in the marginal division with comparison to patches in the neostriatum of the rat brain |
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| Authors: | Chuanxing Wang Si Yun Shu Zhouyi Guo Ye Feng Cai Xinmin Bao Changchun Zeng Bingyi Wu Ziyou Hu Xuemei Liu |
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| Institution: | (1) College of Biophotonics, South China Normal University, Guangzhou, GD, 510631, China;(2) Institute of Cognitive Neuroscience, South China Normal University, Guangzhou, GD, 510631, China;(3) First Department of Neurology, Second Affiliated Hospital, Guangzhou University of Traditional Chinese medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, 510120, China;(4) Research Center of Clinical Medicine, Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China |
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| Abstract: | Background Mu opioid receptor (MOR), which plays key roles in analgesia and also has effects on learning and memory, was reported to
distribute abundantly in the patches of the neostriatum. The marginal division (MrD) of the neostriatum, which located at
the caudomedial border of the neostriatum, was found to stain for enkephalin and substance P immunoreactivities and this region
was found to be involved in learning and memory in our previous study. However, whether MOR also exists in the MrD has not
yet been determined. |
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| Keywords: | Mu opioid receptor Neostriatum Marginal division Patches Immunohistochemistry Western blot |
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