Heteromeric K+ channels in plants |
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Authors: | Lebaudy Anne Hosy Eric Simonneau Thierry Sentenac Hervé Thibaud Jean-Baptiste Dreyer Ingo |
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Affiliation: | Biochimie et Physiologie Moléculaire des Plantes, Unitémixte de Recherche 5004, Centre National de la Recherche Scientifique/Institut National de la Recherche Agronomique (U 386)/Montpellier SupAgro/Université-Montpellier 2, 1 Place Viala, 34060 Montpellier Cedex 1, France;, Laboratoire d'Ecophysiologie des Plantes sous Stress Environnementaux (LEPSE), Unitémixte de Recherche 759, Institut National de la Recherche Agronomique/Montpellier SupAgro, 1 Place Viala, 34060 Montpellier Cedex 1, France;, Institut für Biochemie und Biologie, Universität Potsdam, Molekularbiologie/Heisenberg-Gruppe BPMPB, Karl-Liebknecht-Str. 24/25, Haus 20, D-14476 Potsdam-Golm, Germany |
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Abstract: | Voltage-gated potassium channels of plants are multimeric proteins built of four α-subunits. In the model plant Arabidopsis thaliana , nine genes coding for K+ channel α-subunits have been identified. When co-expressed in heterologous expression systems, most of them display the ability to form heteromeric K+ channels. Till now it was not clear whether plants use this potential of heteromerization to increase the functional diversity of potassium channels. Here, we designed an experimental approach employing different transgenic plant lines that allowed us to prove the existence of heteromeric K+ channels in plants. The chosen strategy might also be useful for investigating the activity and function of other multimeric channel proteins like, for instance, cyclic-nucleotide gated channels, tandem-pore K+ channels and glutamate receptor channels. |
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Keywords: | Arabidopsis potassium channel Kv heteromerization |
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