Autophagy in a Mouse Model of Distal Myopathy with Rimmed Vacuoles or Hereditary Inclusion Body Myopathy |
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Abstract: | In the article Autophagy in a Mouse Model of Distal Myopathy with Rimmed Vacuoles or Hereditary Inclusion Body Myopathy by May Christine V. Malicdan, Satoru Noguchi and Ichizo Nishino (Autophagy 2007; 3:396-8) the authors describe a transgenic mouse that displays the human distal myopathy with rimmed vacuoles (DMRV) phenotype. In this report, the mutation used to generate the mutation was incorrectly written as “V572L” when it should have been “D176V”. Accordingly, the transgenic mice should be named “Gne-/- hGNED176V-Tg”. All of the other data have been verified by repeated experiments. Furthermore, the finding that the mouse phenotype resembles human DMRV, including the presence of autophagy, remains valid. We apologize for any inconvenience this may have caused. |
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