Does an increase in body mass index over 10 years affect knee structure in a population-based cohort study of adult women? |
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| Authors: | Sharon L Brennan Flavia M Cicuttini Julie A Pasco Margaret J Henry Yuanyuan Wang Mark A Kotowicz Geoff C Nicholson Anita E Wluka |
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| Institution: | (1) Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Commercial Road, Melbourne, 3004, Australia;(2) Department of Clinical and Biomedical Sciences: Barwon Health, The University of Melbourne, Ryrie Street, Geelong, 3220, Australia |
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| Abstract: | Introduction Although obesity is a modifiable risk factor for knee osteoarthritis (OA), the effect of weight gain on knee structure in
young and healthy adults has not been examined. The aim of this study was to examine the relationship between body mass index
(BMI), and change in BMI over the preceding 10-year period, and knee structure (cartilage defects, cartilage volume and bone
marrow lesions (BMLs)) in a population-based sample of young to middle-aged females. |
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