Study of an infant brain subjected to periodic motion via a custom experimental apparatus design and finite element modelling |
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| Authors: | J. Cheng I.C. Howard M. Rennison |
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| Affiliation: | 1. School of Mathematical Sciences, Xiamen University, Xiamen, Fujian 361005, China;2. Fujian Provincial Key Laboratory of Mathematical Modeling and High-Performance Scientific Computation, Xiamen University, Xiamen, Fujian 361005 China;3. Department of Mathematical Sciences, Worcester Polytechnic Institute, MA 01609, USA;4. Network Technology Research Institute, China United Network Communications Co., Ltd., Beijing, China;5. Mallinkcrodt Institute of Radiology, Washington University, St. Louis, MO 63110, USA;6. Cardiovascular Division, Washington University, St. Louis, MO 63110, USA;7. School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China;1. CERIS, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal;2. Delft University of Technology, Dept. of Civil Eng. and Geosciences, P.O. Box 5048, 2600 GA Delft, the Netherlands;1. College of Civil Engineering, Hunan University, Changsha 410082, PR China;2. Department of Civil and Environmental Engineering, Michigan Technological University, Houghton, MI 49931, USA;1. IBK Technology, Rehdorfer Strasse, 90431 Nuremberg, Germany;2. University of Leeds, Woodhouse Lane, LS29JT Leeds, UK |
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| Abstract: | This paper presents a rig that was specifically designed to simulate the shaking of mechanical models of biological systems, especially those related to shaken baby syndrome (SBS). The scope of this paper includes the testing of an anthropomorphic model that simulates an infant head and provides validation data for complex finite element (FE) modelling using three numerical methods (Lagrangian, Arbitrary-Lagrangian–Eulerian (ALE) and Eulerian method) for fluid structure coupling.The experiments for this study aim to provide an understanding of the influence of two factors on intracranial brain movement of the infant head during violent shaking: (1) the specific paediatric head structure: the anterior fontanelle and (2) the brain–skull interface.The results show that the Eulerian analysis method has significant advantages for the FSI modelling of brain–CSF–skull interactions over the more commonly used methods, e.g. the Lagrangian method. To the knowledge of the authors, this methodology has not been discussed in previous publication.The results indicate that the biomechanical investigation of SBS can provide more accurate results only if the skull with paediatric features and the brain–skull interface are correctly represented, which were overlooked in previous SBS studies. |
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