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Immunochemical evidence for a gastrin-like peptide in the intestinal tissues of the earthworm Lumbricus terrestris
Affiliation:1. Division of Fluid Dynamics/Division of Energy Technology, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden;2. Division of Fluid Dynamics, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden;3. Haldor Topsøe A/S, Nymøllevej 55, DK-2800 Kgs. Lyngby, Denmark
Abstract:
  • 1.1. The presence of gastrin-like immunoreactive materials in intestinal tissues of the earthworm Lumbricus terrestris has been demonstrated by means of radioimmunoassay technique.
  • 2.2. The greatest activity coincides with the areas of the intestines with high digestive enzyme activities. No gastrin-like activities were detected in nerve tissues.
  • 3.3. The results also indicate that earthworm gut tissues may contain different forms of gastrin or gastrin-like peptides.
  • 4.4. The absence of gastrin-like activity in earthworm nerve tissues may have significant phylogenetic implication for the proposed gastrin-cholecystokinin origin in neuronal elements of invertebrates.
Keywords:
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