Computational Identification of Protein-Protein Interactions in Rice Based on the Predicted Rice Interactome Network |
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| Authors: | Pengcheng Zhu Haibin Gu Yinming Jiao Donglin Huang Ming Chen |
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| Affiliation: | Pengcheng Zhu1,Haibin Gu1,Yinming Jiao1,Donglin Huang1,2,and Ming Chen1,3 1Department of Bioinformatics,College of Life Sciences,Zhejiang University,Hangzhou 310058,China,2James D. Watson Institute of Genome Sciences,3State Key Laboratory of Plant Physiology and Biochemistry |
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| Abstract: | Plant protein-protein interaction networks have not been identified by large-scale experiments. In order to better understand the protein interactions in rice, the Predicted Rice Interactome Network (PRIN; http://bis.zju.edu.cn/ prin/) presented 76,585 predicted interactions involving 5,049 rice proteins. After mapping genomic features of rice (GO annotation, subcellular localization prediction, and gene expression), we found that a well-annotated and biologically significant network is rich enough to captu... |
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| Keywords: | protein-protein interactions rice interactome interolog sub-network expansion pathway clustering |
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