Immunohistochemical localization of nerve growth factor and epidermal growth factor in guinea pig prostate gland |
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| Authors: | H. Shikata N. Utsumi M. Hiramatsu N. Minami N. Nemoto T. Shikata |
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| Affiliation: | (1) Department of Oral Pathology, Josai Dental University, 350-02 Sakado, Saitam, Japan;(2) Department of Dental Pharmacology, Josai Dental University, 350-02 Sakado, Saitam, Japan;(3) Department of Pathology, Nihon University School of Medicine, 173 Itabashi, Tokyo, Japan |
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| Abstract: | Summary Prostate glands of adult guinea pigs were stained for nerve growth factor (NGF) and epidermal growth factor (EGF) by immunohistochemical methods. Both NGF and EGF were localized diffusely in the cytoplasm of the glandular epithelial cells, and also in their secretory products. These findings suggest that NGF and EGF are synthesized, stored, and secreted by the glandular epithelial cells of the prostate. |
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