Ultrastructure of globule leucocyte inclusions in the rat and mouse

Summary The fine structure of the globules in globule leucocytes of rat and mouse infected with various parasites has been studied. Best preservation was obtained with glutaraldehyde and subsequent osmium fixation. It is concluded that the structure of the globules is host specific. In rat, the structure is not parasite specific, but in mouse slight differences in the structure of the globules of the globule leucocyte in different experimental conditions suggest a small change in the packing of the sub-units.The authors are grateful to Professor G. M. Wyburn and Mr. R. N. C. Aitken for research facilities and advice. The work was partially financed by Agricultural Research Council Grant No. AG 17/49.