Simultaneous DSC-FTIR microspectroscopy used to screen and detect the co-crystal formation in real time |
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| Authors: | Wu Tieh-Kang Lin Shan-Yang Lin Hong-Liang Huang Yu-Ting |
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| Affiliation: | Department of Biotechnology, Yuanpei University, Hsin-Chu, Taiwan |
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| Abstract: | We first report that the formation of pharmaceutical co-crystal can be synchronously screened and confirmed by a simultaneous DSC-FTIR microspectroscopic system, in which this combined unique system giving spectroscopic and thermodynamic information could provide a easy and direct way for one step screening and qualitative detection of the co-crystal formation in real time. |
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| Keywords: | Co-crystal DSC-FTIR |
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