An Apparent Connection between Histidine, Recombination, and Repair in Neurospora |
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| Authors: | Dorothy Newmeyer Alice L Schroeder and Donna R Galeazzi |
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| Institution: | Department of Biological Sciences, Stanford University, Stanford, California 94305;Program in Genetics, Washington State University, Pullman, Washington 99163 |
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| Abstract: | Two mutants of Neurospora crassa, uvs-3 and mei-3, share four properties--UV sensitivity, inhibition by histidine, meiotic blockage when homozygous, and increased duplication instability (due to mitotic crossing over, to deletions or to both). The present paper shows that a third nonallelic mutant, uvs-6, exhibits the same four properties.--Also, the instability of duplications in the absence of any UV-sensitive mutant is increased by the presence of histidine in the growth medium. |
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