The BCR signalosome: where cell fate is decided |
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Authors: | Ulivieri C Baldari C T |
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Affiliation: | Department of Evolutionary Biology, University of Siena, Siena, Italy. |
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Abstract: | B cell antigen receptor (BCR) engagement results in the assembly of a multimolecular complex at the cytosolic side of the plasma membrane, known as signalosome. Here we briefly review the current knowledge on the molecules which participate in the BCR signalosome and on the response modulators which control the final signal output by enhancing or dampening BCR signaling. |
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