Comparison of the efficacy of alpha-lactalbumin from equine, bovine, and human milk in the growth of intestinal IEC-6 cells |
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| Authors: | Xijier Mori Yuki Fukuoka Mayuko Cairangzhuoma Inagaki Mizuho Iwamoto Satoshi Yabe Tomio Kanamaru Yoshihiro |
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| Affiliation: | United Graduate School of Agricultural Science, Gifu University, Gifu, Japan. |
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| Abstract: | Native alpha-lactalbumins (α-LA) from equine, bovine, and human milk were not cytotoxic. However, after treatment with trifluoroethanol (TFE), all three α-LAs exhibited cytotoxicity. Toxic potencies were distinctly different among them. Equine α-LA was the most robust, bovine α-LA was moderate, and human α-LA was weak. There were no significant structural changes as between the native and the TFE-treated α-LAs. |
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