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Phospholipid/cholesterol model membranes: formation of cholesterol crystallites
Authors:Diana Bach  Ellen Wachtel
Institution:a Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, 76100 Israel
b Chemical Services Unit, Weizmann Institute of Science, Rehovot, 76100 Israel
Abstract:Experimental data that define conditions under which cholesterol crystallites form in cholesterol/phospholipid model membranes are reviewed. Structural features of the phospholipids that determine cholesterol crystallization include the length and degree of unsaturation of the acyl chains, the presence of charge on the headgroups and interheadgroup hydrogen bonds.
Keywords:Differential scanning calorimetry  X-ray diffraction  Phospholipid  Cholesterol  NMR
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