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Association of plasma viral RNA load with prognosis in cats naturally infected with feline immunodeficiency virus
Authors:Goto Yuko  Nishimura Yoshiaki  Baba Kenji  Mizuno Takuya  Endo Yasuyuki  Masuda Kenichi  Ohno Koichi  Tsujimoto Hajime
Institution:Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Abstract:We measured the quantity of plasma feline immunodeficiency virus (FIV) RNA using a real-time sequence detecting system. Plasma viral RNA load was shown to correlate with the clinical stage, survival time, and disease progression in naturally FIV-infected cats. The present study indicates that the plasma viral RNA load can be used as a clinical marker representing the impairment of the immune system and predicting the clinical outcome in FIV-infected cats.
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