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The Bloom's syndrome helicase: keeping cancer at bay |
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| Authors: | Mohaghegh Payam Hickson Ian D |
| Affiliation: | University of Oxford, UK. |
| Abstract: | Bloom's syndrome, a very rare inherited disorder, predisposes its sufferers to the full range of cancers that afflict humanity. This predisposition is rooted in just one defective gene on chromosome 15. It encodes the BLM helicase - an enzyme that ordinarily protects against DNA damage arising during replication. |
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