Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis |
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Authors: | Tan M W Ausubel F M |
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Affiliation: | Department of Genetics, Department of Molecular Biology, Wellman 10, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA. tan@genetics.mgh.harvard.edu |
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Abstract: | In the past year, a Caenorhabditis elegans-Pseudomonas aeruginosa pathogenesis model has been developed to facilitate the systematic dissection of both host and pathogen genes involved in pathogenic interactions. Analysis of the P. aeruginosa-C. elegans interaction should shed light on the larger question of how organisms interact at the molecular level in antagonistic relationships. |
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