Hypolipidemic, hypoprostatic and pharmacological activity of oxohexaene polyene antibiotic (HA-1-92) |
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Authors: | Naik S R Harindran J |
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Affiliation: | Research & Development Division, Hindustan Antibiotics Limited, Pimpri, Pune 411 018, India. |
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Abstract: | HA-1-92, a new oxohexaene polyene macrolide showed significant hypolipidemic and hypoprostatic activity both in rat and rabbit models. HA-1-92 did not elicit significant effect on blood pressure or respiration in anaesthetized rat or on various isolated tissue preparation studies. |
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