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| 乳链菌肽作用机制及其应用 | |
| 引用本文： | 牛畅,田晓琴,袁静. 乳链菌肽作用机制及其应用[J]. 生物技术通讯, 2006, 17(5): 810-813 |
| 作者姓名： | 牛畅 田晓琴 袁静 |
| 作者单位： | 1. 西北农林科技大学,生命科学学院,陕西,杨凌,712100 2. 西北农林科技大学,食品科学与工程学院,陕西,杨凌,712100 3. 西北农林科技大学,食品科学与工程学院,陕西,杨凌,712100;军事医学科学院,生物工程研究所,北京,100071 |
| 基金项目： | 西北农林科技大学校青年基金 |
| 摘 要： | 乳链菌肽作为高效、安全的天然食品防腐剂已得到广泛应用。成熟的乳链菌肽含有34个氨基酸残基,由5个硫醚桥组成独特的内环结构,是研究蛋白质结构与功能的一个很好的材料。本文论述了乳链菌肽的分子结构及其与细胞膜作用的分子机制,详细阐述了乳链菌肽的作用模型。 |
| 关 键 词： | 乳链菌肽 分子分析 作用机制 |
| 文章编号： | 1009-0002(2006)05-0810-04 |
| 收稿时间： | 2006-03-02 |
| 修稿时间： | 2006-03-02 |
Antimicrobial Mechanism of Nisin and its Application |
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| NIU Chang,TIAN Xiao-qin,YUAN Jing. Antimicrobial Mechanism of Nisin and its Application[J]. Letters in Biotechnology, 2006, 17(5): 810-813 | |
| Authors: | NIU Chang TIAN Xiao-qin YUAN Jing |
| Affiliation: | 1. a. College of Life Sciences; b. College of Food Science and Engineering; Northwest Sci-Tech University of Agriculture and Forestry, Yangling 712100; 2. Beijing Institute of Biotechnology, Beijing 100071; China |
| Abstract: | Nisin, a 34-residue antibacterial peptide, is widely utilized in food industry as highly effective, safe and natural food preservative. It contains cyclic lanthionine rings and unusual dehydrated amino acids, which are formed by posttranslational modification. The strucure of nisin is usually used to study on the relationship of structure-function. In this paper the molecule structure and the interaction mechanism with target membrane of nisin, and the mode for nisin pore formation were described. |
| Keywords: | nisin molecule analysis mechanism of action |
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