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New method of lysophospholipid incorporation into biological membranes. Effect of lysophosphatidylcholine on the activity of membrane-bound enzymes
Authors:E V Diatlovitskaia  A F Lemenovskaia  A T Valdnietse  E V Sinitsyna  L D Bergel'son
Abstract:The incorporation of lysophosphatidylcholine into biological membranes and its effect on some membrane-bound enzymes of mitochondria and microsomes from rat liver and hepatoma were studied. It was shown that in the presence of lipid-exchange proteins of the liver a far greater amount of lysophosphatidylcholine is incorporated into the membranes than in the-iv absence. The increase of the lysophosphatidylcholine content in the membranes has no effect on the activity of mitochondrial monoamine oxidase, inhibits the activity of microsomal cytochrome P-450 and activates glucose-6-phosphatase.
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