Evasion from NK cell-mediated immune responses by HIV-1 |
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Authors: | Jost Stephanie Altfeld Marcus |
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Affiliation: | Ragon Institute of MGH, MIT and Harvard, Bldg. 149, 13th Street, 6th Floor, Charlestown, MA 02129, USA. |
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Abstract: | Human immunodeficiency virus type 1 (HIV-1) mostly owes its success to its ability to evade host immune responses. Understanding viral immune escape mechanisms is a prerequisite to improve future HIV-1 vaccine design. This review focuses on the strategies that HIV-1 has evolved to evade recognition by natural killer (NK) cells. |
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