Peroxidation of lipids from liver mitochondria during pneumonia

Inflammation of the respiratory system leads to an increase in the relative content of lipids in the liver mitochondria and to an activation of initial stages of their peroxidation. Antioxidative activity of the postmitochondrial liver fraction is in the inverse relation to the concentration of acyl residues with the conjugated diene structures. But the malonic dialdehyde level decreases during the lung inflammation development from 3 days to 3 months. These changes may be explained by respiratory mitochondria chain reconstruction due to an increase in the lipid utilization in the oxidative phosphorylation reactions.