VARAN: a web server for variability analysis of DNA microarray experiments |
| |
Authors: | Golfier G Dang M Tran Dauphinot L Graison E Rossier J Potier M-C |
| |
Institution: | Neurobiologie et Diversité Cellulaire, CNRS UMR7637, Ecole Supérieure de Physique et de Chimie Industrielles, 10 rue Vauquelin, 75005 Paris, France. geoffroy.golfier@espci.fr |
| |
Abstract: | SUMMARY: Here, we describe a tool for VARiability Analysis of DNA microarrays experiments (VARAN), a freely available Web server that performs a signal intensity based analysis of the log2 expression ratio variability deduced from DNA microarray data (one or two channels). Two modules are proposed: VARAN generator to compute a sliding windows analysis of the experimental variability (mean and SD) and VARAN analyzer to compare experimental data with an asymptotic variability model previously built with the generator module from control experiments. Both modules provide normalized intensity signals with five possible methods, log ratio values and a list of genes showing significant variations between conditions. AVAILABILITY: http://www.bionet.espci.fr/varan/ SUPPLEMENTARY INFORMATION: http://www.bionet.espci.fr/varan/help.html |
| |
Keywords: | |
本文献已被 PubMed Oxford 等数据库收录! |
|