Vitamin E inhibits protein oxidation in skeletal muscle of resting and exercised rats. |
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Authors: | A Z Reznick E Witt M Matsumoto L Packer |
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Institution: | Department of Morphological Sciences, Technion Faculty of Medicine, Haifa, Israel. |
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Abstract: | It is well known that exercise induces lipid peroxidation in skeletal muscle and that vitamin E prevents exercise-induced lipid damage. In this study we show for the first time, an increase in protein oxidation in skeletal muscle after a single bout of exercise, related to an exercise-induced decrease in lipophilic antioxidants, and substantial protection against both resting and exercise-induced protein oxidation by supplementation with various isomers (alpha-tocopherol, alpha-tocotrienol) of vitamin E. |
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