Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning |
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| Authors: | Alexander Bartelt,Clara Weigelt,M. Lisa Cherradi,Andreas Niemeier,Klaus Tö dter,Joerg Heeren,Ludger Scheja |
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| Affiliation: | 1. Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistr, 52, 20246 Hamburg, Germany;2. Department of Orthopedics, University Medical Center Hamburg-Eppendorf, Martinistr, 52, 20246 Hamburg, Germany |
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| Abstract: | |
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| Keywords: | Acaca, acetyl CoA carboxylase-α aLKO, adipocyte LPL knockout BAT, brown adipose tissue Dio2, type 2 thyroid hormone deiodinase ChREBP, carbohydrate response element binding protein COX-2, cyclooxygenase-2 DNL, de novo lipogenesis Elovl, fatty acid elongase Fasn, fatty acid synthase FPLC, fast performance liquid chromatography Glut4, glucose transporter 4 LPL, lipoprotein lipase GPIHBP1, glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 HFD, high-fat diet Pgc1a, peroxisome proliferator activator receptors gamma coactivator-1-α PUFA, polyunsaturated fatty acids Scd1, stearoyl CoA desaturase-1 SEM, standard error of mean SREBP1c, sterol regulatory element binding protein 1c Tbp, TATA box binding protein TG, triglycerides TRL, triglyceride-rich lipoproteins WT, wild type WAT, white adipose tissue iWAT, inguinal WAT gWAT, gonadal WAT Ucp1, uncoupling protein 1 |
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