Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1 |
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| Authors: | Norma Morrison Stephen B. Harrap Jeffrey L. Arriza Elizabeth Boyd J. Michael Connor |
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| Affiliation: | (1) Duncan Guthrie Institute of Medical Genetics, Yorkhill, G3 8SJ Glasgow, UK;(2) MRC Blood Pressure Unit, Western Infirmary, G11 6NT Glasgow, UK;(3) Gene Expression Laboratory, The Salk Institute for Biological Studies, P.O.Box 85800, 92138 San Diego, CA, USA |
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| Abstract: | Summary The gene for human mineralocorticoid receptor (hMR), previously mapped to chromosome 4, has been further localized to 4q31.1 by in situ hybridization using a biotinylated 3.75kb human cDNA clone encoding the primary amino acid sequence of hMR as a probe. Preliminary comparative mapping studies in orangutan (Pongo pygmaeus) suggest localization of the probe to the long arm of chromosome 3. |
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