The role of the cell cycle in differentiation of the cellular slime mould Dictyostelium discoideum |
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| Authors: | Paul T. Sharpe D. J. Watts |
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| Affiliation: | (1) Department of Biochemistry, University of Sheffield, Sheffield, UK;(2) Department of Biochemistry, University of Sheffield, SIO 2TN Sheffield, UK |
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| Abstract: | Summary During development and differentiation of the cellular slime mould Dictyostelium discoideum there appears to be a relationship between the cell cycle and cell fate: amoebae halted in G2 phase during early development differentiate into spores whereas stalk cells are formed from amoebae halted in GI phase. It is proposed that this is because a major effect of the cell cycle is to generate heterogeneity in the cell surface properties of the developing amoebae. |
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| Keywords: | cell cycle Dictyostelium discoideum differentiation |
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