Protease resistant interleukin-3 stimulating components in excretory and secretory products from adult worms of Strongyloides ratti. |
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Authors: | T Abe Y Nawa K Yoshimura |
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Affiliation: | Department of Parasitology, Akita University School of Medicine, Japan. |
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Abstract: | Excretory and secretory (ES) products collected from adult worms of Strongyloides ratti stimulated interleukin-3 (IL-3) production with mesenteric lymph node cells from infected C57BL/6 mice, but not with normal mesenteric lymph node cells. The IL-3 stimulating components were not major IgG binding antigens. Activity of the IL-3 stimulating components was stable by treatment with protease, although reduced by heating in boiling water. |
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