| 现代系统生物技术与图式遗传学 |
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| 引用本文： | 曾邦哲. 现代系统生物技术与图式遗传学[J]. 生物技术通报, 2007, 0(1): 1-4,27 |
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| 作者姓名： | 曾邦哲 |
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| 作者单位： | 中国科学院微生物研究所基因工程技术中心,北京,100080 |
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| 摘 要： | 基因组程序化表达调控与生物体形态结构发生的相互对应是图式遗传学和系统生物技术研究复杂生物系统的核心。基因-蛋白质表达与神经-内分泌信号,构成生物系统发生演变的双向调控过程是生物信息控制系统的结构、功能和演变的基础。细胞信号传导与基因差异表达调控是从基因、细胞到器官的细胞动力学转换系统,是基因、蛋白质、脂类等生物高分子相互作用与细胞再生、分化、迁移、凋亡的程序化调控节律,也就是基因定位图谱-细胞定位图谱的基因组-蛋白质组与生物体的细胞节律-形态的发生转换过程。
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| 关 键 词： | 生物系统 图式遗传学 系统生物技术 信号生物学 基因表达 |
| 修稿时间： | 2006-12-11 |
The Pattern Genetics and Modern System Biotechnology |
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| Zeng Bangzhe. The Pattern Genetics and Modern System Biotechnology[J]. Biotechnology Bulletin, 2007, 0(1): 1-4,27 |
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| Authors: | Zeng Bangzhe |
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| Affiliation: | Gene Engineering Technological Center,Institute of Microbiology,CAS,Beijing 100080 |
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| Abstract: | Morphogenesis of organism is controlled by the program expression of genome,it to be the core field of complex biosystem study of pattern genetics and system biotechnology.Gene-protein expression and neuron-endocrine signaling,construct the bi-direction regulation of biosystem development and evolution,and is the structural,functional,evolutional foundation of central biological information control system.Cell signal transduction and gene differential expression,is the transformation system of cell dynamics of gene regulation of morphogenesis,which forms the cybernetic rhythm of bio-molecules interaction and cell proliferation,differentiation,migrant and apoptosis.Rhythm-shape transformation system means the correction between the genes-proteins map in genome-proteome to the cells cycle-cytogenesis map in organism. |
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| Keywords: | Biosystem Pattern genetics Signal biology Gene expression |
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