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铜绿假单胞菌菌苗对尿路感染的免疫功能调节
引用本文:孙文平,牟希亚,高小平,陈艳君,谭梅. 铜绿假单胞菌菌苗对尿路感染的免疫功能调节[J]. 微生物学杂志, 2002, 22(4): 20-21
作者姓名:孙文平  牟希亚  高小平  陈艳君  谭梅
作者单位:1. 大连医科大学,微生物学教研室,辽宁,大连,116027
2. 大连医科大学,第二临床学院检验科,辽宁,大连,116023
3. 大连市友谊医院,检验科,辽宁,大连,116011
摘    要:铜绿假单胞菌菌苗是一种新型的细菌性免疫调节剂。用其治疗反复发作性尿路感染 ,其中体液免疫检测结果实验组治疗后的广谱抗体效价比治疗前的广谱抗体效价提高 8~ 6 4倍 ,细胞免疫的检测中T细胞亚群中各项指标治疗前后均有显著性差异 (P <0 .0 1)。提示 ,该菌苗是通过调整患者自身的体液免疫和细胞免疫功能 ,从而达到治疗效果

关 键 词:铜绿假单胞菌菌苗  反复发作性尿路感染  免疫调节
文章编号:1005-7021(2002)04-0020-02
修稿时间:2001-09-14

Immune Modification of Pseudomonas aeruginosa Vaccine in Urethral Infection
SUN Wenping+,MOU Xiya+,GAO Xiaoping+,CHEN Yanjun+,TAN Mei+. Immune Modification of Pseudomonas aeruginosa Vaccine in Urethral Infection[J]. Journal of Microbiology, 2002, 22(4): 20-21
Authors:SUN Wenping+  MOU Xiya+  GAO Xiaoping+  CHEN Yanjun+  TAN Mei+
Affiliation:SUN Wenping+1,MOU Xiya+1,GAO Xiaoping+2,CHEN Yanjun+2,TAN Mei+3
Abstract:Vaccine of Pseudomonas aeruginosa strain is a new kind bacterial immune modifier.The application of it in treating recurrent urethral infection has good results, among which the humoral detection of experiment groups treated by the Pseudomonas aeruginosa mannose sensitive haemagglutination that the titer of wide spectrum antibodies after the application was 8 to 64 times that of the pretreated groups. In the detection of cellular immune, various indexes of T cell subgroups after the treatment showed remarkable difference (P> 0.01) as compared with that of pretreated groups. These suggested that vaccine of P.aeruginosa treated the patients by modifying the humoral immune and cellular immune functions.;
Keywords:Pseudomonas aeruginosa mannose sensitive haemagglutination   recurrent urethral infection   immune modification.
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