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Chromosome evolution in the cercopithecidae and its relationship to human fragile sites and neoplasia |
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| Authors: | I C Clemente M Ponsà M Garcia J Egozcue |
| Institution: | (1) Department of Cellular Biology and Physiology, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain;(2) Institut de Biologia Fonamental  Vicent Villar Palasi , Univesitat Autònoma de Barcelona, 08193 Bellaterra, Spain;(3) Present address: Departamento de Psiquiatria y Psibiologia Clinica, Universidad de Barcelona, Barcelona, Spain |
| Abstract: | Seven species of the family Cercopithecidae have been studied using highresolution banding techniques. Comparative studies allowed us to identify the main chromosomal reorganizations in this group, as well as to establish the phylogenetic relationships between species. Some of the regions involved in evolutionary rearrangements correspond to human fragile sites and/or chromosomal rearrangements related to neoplasia. |
| Keywords: | Cercopithecidae chromosome banding fragile sites heterochromatin latent centromeres chromosome evolution |
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