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Asymmetric organocatalysis with glycosyl-beta-amino acids: direct asymmetric aldol reaction of acetone with aldehydes
Authors:Dwivedi Namrata  Bisht Surendra S  Tripathi Rama P
Institution:Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India.
Abstract:Direct asymmetric aldol reaction of acetone with aromatic aldehydes was achieved in good yields and high enantioselectivity using 5-amino-5-deoxy-beta-L-ido-(alpha-D-gluco)-heptofuranuronic acids as a new class of organocatalysts.
Keywords:Asymmetric catalysis  Aldol reactions  Glycosylamino acids  5-Amino-5-deoxy-heptofuranuronic acids
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