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The location of non-specific esterase in human lung macrophages
Authors:F. Jaubert  J. P. Monnet  C. Danel  J. Chretien  C. Nezelof
Affiliation:(1) Groupe de Pathologie Pédiatrique U 77, Hôpital Necker, 149, rue de Sèvres, F-75730 Paris Cedex 15, France;(2) Clinique de Pneumophtisiologie, Hôpital Laennec, 42, rue de Sèvres, F-75007 Paris, France
Abstract:Summary The non-specific carboxyl (serine) esterase of the human pulmonary alveolar macrophage was localized ultrastructurally using agr-naphthyl acetate and hexazotized pararosanilin. The reaction product principally outlined the outer side of the plasma membrane. Consequently, this esterase is an ectoenzyme which may function as mediator of cell response to injurious agents from the outside.
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