Serological cross-reactivity between products of different Ia loci |
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| Authors: | Philip A Lowry Donal B Murphy |
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| Institution: | (1) Yale University, School of Medicine, 310 Cedar Street, 06510 New Haven, Connecticut, USA |
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| Abstract: | Antibody prepared in I-E-subregion-incompatible strains (anti-A
e
s
:E
/k
) cross-reacts with I-A-subregion controlled A
b
: A
/b
and A
q
A
q
complexes. This cross-reaction defines a new I-region specificity designated Ia.50. The implications of this finding for the genetic origin of the I region and immuneresponse-gene function are discussed. |
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| Keywords: | |
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