Study of the effect of seven-day immersion on the excretory function of the kidneys

The excretion of total protein, creatinine, urea, uric acid, glucose, potassium, sodium, calcium, phosphorus, and magnesium, as well as the uroproteinogram (12 groups of proteins) and uroenzymogram (five enzymes) parameters, was studied in the experiment with seven-day immersion in eight men aged 21–26 years. The results of the study allow a conclusion that seven-day immersion did not lead to any unfavorable changes in the renal function. The study of the uroproteinogram showed the absence of shifts in either glomerular filtration or tubular reabsorption, which agrees with the absence of significant changes in the uroenzymogram values. Even in significantly increased diuresis, the physiological norm of protein and glucose excretion was not exceeded; the electrolyte excretion was normalized quickly enough. An increased excretion of creatinine, urea, calcium, magnesium, and phosphorus appears to reflect activation of catabolic processes in skeletal muscles.